- Sunil Varma (9 movies)
- Samuthirakani (7 movies)
- S. J. Suryah (6 movies)
- Sathyaraj (4 movies)
- Sharad Kelkar (4 movies)
- Sydney Sweeney (4 movies)
- Sai Kumar (3 movies)
- Sanjay Dutt (3 movies)
- Sanjay Mishra (3 movies)
- Sanya Malhotra (3 movies)
- Shah Rukh Khan (3 movies)
- Siddharth (3 movies)
- Sivakarthikeyan (3 movies)
- Sonam Bajwa (3 movies)
- Supergood Subramani (3 movies)
- Surabhi Prabhavathi (3 movies)
- Suresh Chakravarthy (3 movies)
- Salman Khan (2 movies)
- Sam Worthington (2 movies)
- Samyuktha (2 movies)
- Sapna Sand (2 movies)
- Sara Ali Khan (2 movies)
- Saravana Subbiah (2 movies)
- Sartaaj Kakkar (2 movies)
- Sathish (2 movies)
- Satya (2 movies)
- Saurabh Sachdeva (2 movies)
- Saurabh Shukla (2 movies)
- Sayaji Shinde (2 movies)
- Scarlett Johansson (2 movies)
- Seth Rogen (2 movies)
- Shahid Latief (2 movies)
- Shakriya Tarinyawat (2 movies)
- Sharat Saxena (2 movies)
- Sharib Hashmi (2 movies)
- Sharvari Wagh (2 movies)
- Shea Whigham (2 movies)
- Shebin Benson (2 movies)
- Sheeba Chaddha (2 movies)
- Shinda Grewal (2 movies)
- Shine Tom Chacko (2 movies)
- Shishir Sharma (2 movies)
- Shivraj Walvekar (2 movies)
- Shreyas Talpade (2 movies)
- Shruti Haasan (2 movies)
- Shruti Marathe (2 movies)
- Siddhant Chaturvedi (2 movies)
- Sikandar Kher (2 movies)
- Simran (2 movies)
- Sofia Boutella (2 movies)